Skip to main content

Table 1 Previous studies of pathological complete response of locally advanced colon cancer after neoadjuvant chemoradiotherapy

From: Pathological complete response of locally advanced colon cancer after preoperative radiotherapy: a case report and narrative review of the literature

Reference Inclusion period No. of participants Location of cancer Regimen of chemotherapy RT (Gy/Fr) R0 (%) pCR (%) OS (%/year) DFS (%/year)
Huang [10], Taiwan 2012–2016 36 Any part of colon FOLFOX 45–50.4/25–28 31/34 (91.2%) 9/34 (26.4%) 88.7%/2 73.6%/2
Qiu [11], China 2010–2012 21 Sigmoid colon Capecitabine based 46–50/23–25 20/21 (95.2%) 8/21 (38.1%) 100%/3 88.9%/3
Cukier [12], Canada 2000–2009 33 Any part of colon 5-FU based 36–50.4/18–28 33/33 (100%) 1/33 (3.0%) 85.9%/3 73.7%/3
  1. RT radiotherapy, pCR pathological complete response, OS overall survival, DFS disease-free survival, FOLFOX folinic acid, 5-fluorouracil and oxaliplatin, 5-FU 5-fluorouracil