Table 1 Previous studies of pathological complete response of locally advanced colon cancer after neoadjuvant chemoradiotherapy
Reference | Inclusion period | No. of participants | Location of cancer | Regimen of chemotherapy | RT (Gy/Fr) | R0 (%) | pCR (%) | OS (%/year) | DFS (%/year) |
|---|---|---|---|---|---|---|---|---|---|
Huang [10], Taiwan | 2012–2016 | 36 | Any part of colon | FOLFOX | 45–50.4/25–28 | 31/34 (91.2%) | 9/34 (26.4%) | 88.7%/2 | 73.6%/2 |
Qiu [11], China | 2010–2012 | 21 | Sigmoid colon | Capecitabine based | 46–50/23–25 | 20/21 (95.2%) | 8/21 (38.1%) | 100%/3 | 88.9%/3 |
Cukier [12], Canada | 2000–2009 | 33 | Any part of colon | 5-FU based | 36–50.4/18–28 | 33/33 (100%) | 1/33 (3.0%) | 85.9%/3 | 73.7%/3 |