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Table 4 Clinical characteristics of the 5 Carney Complex patients with thyroid lesion reported in Japan

From: Carney complex: a case with thyroid follicular adenoma without a PRKAR1A mutation

No. Author/Year/Ref. no. Age(y)/Sex Family history Carney complex manifestations PRKAR1A mutation
1 Ando et al./2015/ [9] 72/F no Thyroid tumor, lentigines, pituitary adenoma (TSH-producing tumor) NA
2 Okamoto et al./2017/ [8] 73/F no Thyroid tumor, lentigines, pituitary adenoma (TSH-producing tumor) none
3 Kako et al./1999/ [11] 47/F no Thyroid tumor, lentigines, cardiac myxoma, PPNAD NA
4 Yamashita et al./2015/ [10] 20/F no Thyroid tumor, breast myxoma, cardiac myxoma, PPNAD, acromegaly NA
5 Our case/2017 69/F no Thyroid tumor, cardiac myxoma none
  1. TSH thyroid stimulating hormone; PPNAD primary pigmented nodular adrenocortical disease; NA not available