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Table 2 Clinical manifestations of Carney Complex in previous reports

From: Carney complex: a case with thyroid follicular adenoma without a PRKAR1A mutation

  Carney [4])/1985
n=40
Stratakis [3]/2001
n=338
Correa [5]/2015
n=750
Gender
 Male 40 43 37
 Female 60 57 63
Family history 25 70 70
Clinical manifestations
 Spotty skin pigmentation 65 77 70-80
 Cardiac myxoma 72 53 20-40
 Cutaneous myxoma 45 33 30-50
 Primary pigmented nodular adrenocortical disease (PPNAD) 45 26 25-60
 Large-cell calcifying Sertoli cell tumor or steroid-type tumor or both 56 33 41
 Mammary myxomatosis or fibroadenoma 42 3 20
 Pituitary adenoma (acromegaly) 10 10 75
 Thyroid tumors 0 5 75
 Osteochondromyxoma 0 2 rare
 Psammomatous melanotic schwannoma 5 10 10
 Blue nevus 0 0 75
Mutation of PRKAR1A gene NA 41 70-80
  1. The table gives the percentage of CNC patients
  2. NA not available