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Surgical Case Reports
Fig. 5 | Surgical Case Reports

Fig. 5

From: Successful local treatment for repeated hepatic recurrences of cholangiolocellular carcinoma: a report on a long-term survivor

Fig. 5

Histological findings of the recurrent lesion. a Small gland-forming cells proliferate in an anastomosing pattern with abundant fibrous stroma (HE staining, ×200). b The tumor cells (T) proliferate as they replace the noncancerous liver parenchyma (N) without tumor capsule (arrow) (HE staining, ×100). c–g Immunohistochemical studies show that the tumor cells are positive for cytokeratin (CK) 7 and CK19 and negative for neural cell adhesion (NCAM), HepPar1, and S100P. h Epithelial membrane antigen (EMA) stain shows positivity at the apical membranous areas of the ducts

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