Fig. 6From: Pancreatic neuroendocrine tumor with complete replacement of the pancreas by serous cystic neoplasms in a patient with von Hippel-Lindau disease: a case reportMicroscopically, the tumor in the tail of the pancreas showed a trabecular architecture with salt-and-pepper chromatin, eosinophilic cytoplasm, and abundant microvasculature (a). The cysts were serous cystadenomas lined with glycogen-rich cuboidal to flattened epithelial cells with clear cytoplasm and uniform round nuclei (b). Immunohistochemically, the tumor cells stained positive for synaptophysin (c) and focally positive for chromogranin A (d). The Ki-67 labeling index was 1% (e)Back to article page