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Table 1 Summary of reported surgical cases of neuroendocrine carcinoma

From: Combination therapies for primary hepatic neuroendocrine carcinoma: a case report

First author (year) ref Age/sex Symptom Treatment Tumor size Details of Recurrence Details of Treatment after Outcome Survival
before surgery (cm) Metastasis (months) recurrence recurrence   (months)
Hsueh (1983) [2] 8/F Dizziness, fatigue Chemotherapy 17 LN, lung None None None Died 4
Zanconati (1996) [4] 4 56/M Abdominal discomfort,Jaundice None 5 ND 3 Liver None Died 5
Pilichowska (1999) [7] 7 57/M Hypochondria mass None 8.2 Lung ND Liver None Died 16
Ishida (2003) [10] 10 72/M None None 3 LN ND ND None ND ND
Garcia (2006) [11] 11 50/M None None 5 None 4 Liver, mesenteric TACE and Chemotherapy Died 16
Yang (2009) [13] 13 65/M Epigastric pain None 7.5 LN 3 Liver None Died 12
  56/F None None ND None None None ND Alive 36.9
  68//F Fatigue None ND None None None ND Alive 18
  51/F None Chemotherapy ND None 6.2 ND ND Alive 15.2
Akahoshi (2010) [14] 14 64/M None None 1.5 None None None ND Alive 3
Huang (2010) [15] 15 51/M Abdominal pain TACE ND(Multiple) None 48 Liver ND Alive 107
  34/M Medical exam TACE ND(Multiple) None None None ND Alive 98
  52/F Diarrhea None ND(Multiple) None 5 liver ND Alive 47
  59/M Medical exam None ND None None None None Alive 34
  54/M Medical exam None ND None None None None Alive 24
  43/M Abdominal pain None ND(Multiple) None None None None Alive 15
  50/F Medical exam None ND(Multiple) None 5 Liver ND Alive 14
  37/M Diarrhea None ND(Multiple) None 1 Liver PEIT Alive 13
  58/F Medical exam None ND None 39 ND ND Alive 148
  56/F Medical exam None ND(Multiple) None 5 Liver ND Alive 33
  50/M Medical exam None ND(Multiple) None 3 Liver ND Alive 12
Shinkawa (2013) [19] 19 73/M Medical exam None 5 None 4 Bone,LN ND Died 6
Kim (2013) [21] 20 67/F nausea None 9 LN None None None Alive 3
Kano (2014) [22] 22 73/M Medical exam None 3 LN 6 Liver Chemotherapy Alive 10
Sotiropoulos (2014) [23] 23 19/F Symptomatic liver mass None 27 None None None None Alive 24
Aboelenen (2014) [24] 24 51/M Abdominal pain None 20 None None None None Alive 6
Wang (2014) * [26] 26           
  1. ND not discribed, LN lymph node, TACE transcatheter arterial chemoembolization, PEIT percutaneous ethanol injection therapy
  2. *There are 8 surgical cases, but personal information are not described