Fig. 2

Paget cells were scattered in squamous epithelium (arrow head) (a) (HE ×200). Adenocarcinoma tissue was observed in the submucosa (b) (HE, ×200). Immunohistochemical staining revealed that CK7, CK20, and CEA expression was positive in epithelial Paget cells and submucosal adenocarcinoma tissues. However, GCDFP-15 activity was not detected in any lesions (c) (×200)