Fig. 2

Clinicopathological findings of case 2. a Continuous papules measuring 15 × 11 mm with telangiectasia were present on the right side of the cheek (black arrow). b Positron emission tomography/computed tomography showed intense tracer uptake (maximum standardized uptake value = 36.8) at the sigmoid colon (white arrow). c Colonoscopy showed an ulcerated hemorrhagic type 2 tumor at the sigmoid colon. d Pathological examination of the sigmoid colon tumor revealed heterogeneity of well-differentiated adenocarcinoma, moderately differentiated adenocarcinoma, and mucinous adenocarcinoma (hematoxylin and eosin stain (H.E.), ×100). e Pathological examination of the tumor on the right cheek revealed sebaceous carcinoma (H.E., ×200)