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Table 1 Reported cases of neuroendocrine carcinoma of the extrahepatic bile duct. Review of the literature

From: Large-cell neuroendocrine carcinoma of the common bile duct: a case report and a review of literature

No. Author Age Sex Histology Location Size Treatment Prognosis
1 Sabanathan [3] 67 M SCNEC Bm 5 cm Palliative bypass and chemo. 6 m, alive
2 Van der Wal [4] 55 M SCNEC + Adenoca. Bm 4 cm Resection N.A.
3 Nishihara [5] 64 M SCNEC + Adenoca. Bh-Bs 1.9 cm Resection 8 m, alive
4 Yamamoto [6] 71 F SCNEC + Adenoca. Bh 6 cm Resection 8 m, dead
5 Kim [7] 64 M SCNEC + Adenoca. Bm 3 cm Resection 1 m, alive
6 Miyashita [8] 85 F SCNEC Bi 3 cm Palliative bypass 5 m, dead
7 Edakuni [9] 82 F SCNEC + Adenoca. Bm 6 cm Resection 45 m, alive
8 Kuraoka [10] 75 M SCNEC Bi 4.5 cm Resection 5 m, alive
9 Hazama [11] 60 M SCNEC CBD 0.3 cm NAC and resection 12 m, dead
10 Arakura [12] 70 F SCNEC Bm 3 cm Resection and chemo. 14 m, dead
11 Park [13] 60 F SCNEC Bs-Bm 3 cm Resection 5 m, dead
12 Thomas [14] 54 M SCNEC Bh-Bm N.A. Resection 6 m, alive
13 Kaiho [15] 66 F SCNEC + Adenoca. Bm 3.5 cm Resection and chemo. 8 m, dead
14 Sato [16] 68 M LCNEC + Adenoca. Bi 2 cm Resection and chemo. 3 m, dead
15 Viana Miguel [17] 76 M SCNEC Bm N.A. Resection, chemo., and irradiation 5 m, alive
16 Jeon [18] 65 M SCNEC Bs-Bm 2 cm Resection and chemo. 12 m, dead
17 Nakai [19] 32 M SCNEC CBD N.A. N.A. N.A. (autopsy)
18 Arakura [20] 75 M SCNEC Bh-Bs 6.5 cm Chemo. and irradiation 10 m, dead
19 Hosonuma [21] 69 F SCNEC Bs-Bm 3 cm Biliary drainage 2 m, alive
20 Okamura [22] 62 M SCNEC Bm 3 cm NAC, resection, and irradiation 20 m, dead
21 Yamaguchi [23] 77 F NEC Bi N.A. Resection and chemo. 27 m, alive
22 Demoreuil [24] 73 M LCNEC + Adenoca. Bh-Bs 3 cm Resection and chemo. 12 m, dead
23 Cho [25] 59 F SCNEC Bm 3 cm Resection 6 m, dead
24 Sasatomi [26] 76 M LCNEC Bh-Bs 5 cm Resection 21 days, dead
25 Ninomiya [27] 75 F LCNEC Bm 3 cm Resection 14 m, alive
26 Park [28] 75 F LCNEC Bm 2.7 cm Resection and chemo. 12 m, dead
27 Kihara [29] 70 F SCNEC Bh 5 cm Resection and chemo. 10 m, alive
28 Current report 79 M LCNEC + Adenoca. Pm 2.9 cm Resection 3 m, dead
  1. NEC neuroendocrine carcinoma, NAC neoadjuvant chemotherapy, Adenoca. adenocarcinoma, CBD common bile duct, Bh hilar bile duct, Bs superior portion of common bile duct, Bm mid-portion of bile duct, Bi inferior portion of bile duct, chemo. chemotherapy, N.A. not available
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