Table 1 Reported cases of neuroendocrine carcinoma of the extrahepatic bile duct. Review of the literature
No. | Author | Age | Sex | Histology | Location | Size | Treatment | Prognosis |
|---|---|---|---|---|---|---|---|---|
1 | Sabanathan [3] | 67 | M | SCNEC | Bm | 5 cm | Palliative bypass and chemo. | 6 m, alive |
2 | Van der Wal [4] | 55 | M | SCNEC + Adenoca. | Bm | 4 cm | Resection | N.A. |
3 | Nishihara [5] | 64 | M | SCNEC + Adenoca. | Bh-Bs | 1.9 cm | Resection | 8 m, alive |
4 | Yamamoto [6] | 71 | F | SCNEC + Adenoca. | Bh | 6 cm | Resection | 8 m, dead |
5 | Kim [7] | 64 | M | SCNEC + Adenoca. | Bm | 3 cm | Resection | 1 m, alive |
6 | Miyashita [8] | 85 | F | SCNEC | Bi | 3 cm | Palliative bypass | 5 m, dead |
7 | Edakuni [9] | 82 | F | SCNEC + Adenoca. | Bm | 6 cm | Resection | 45 m, alive |
8 | Kuraoka [10] | 75 | M | SCNEC | Bi | 4.5 cm | Resection | 5 m, alive |
9 | Hazama [11] | 60 | M | SCNEC | CBD | 0.3 cm | NAC and resection | 12 m, dead |
10 | Arakura [12] | 70 | F | SCNEC | Bm | 3 cm | Resection and chemo. | 14 m, dead |
11 | Park [13] | 60 | F | SCNEC | Bs-Bm | 3 cm | Resection | 5 m, dead |
12 | Thomas [14] | 54 | M | SCNEC | Bh-Bm | N.A. | Resection | 6 m, alive |
13 | Kaiho [15] | 66 | F | SCNEC + Adenoca. | Bm | 3.5 cm | Resection and chemo. | 8 m, dead |
14 | Sato [16] | 68 | M | LCNEC + Adenoca. | Bi | 2 cm | Resection and chemo. | 3 m, dead |
15 | Viana Miguel [17] | 76 | M | SCNEC | Bm | N.A. | Resection, chemo., and irradiation | 5 m, alive |
16 | Jeon [18] | 65 | M | SCNEC | Bs-Bm | 2 cm | Resection and chemo. | 12 m, dead |
17 | Nakai [19] | 32 | M | SCNEC | CBD | N.A. | N.A. | N.A. (autopsy) |
18 | Arakura [20] | 75 | M | SCNEC | Bh-Bs | 6.5 cm | Chemo. and irradiation | 10 m, dead |
19 | Hosonuma [21] | 69 | F | SCNEC | Bs-Bm | 3 cm | Biliary drainage | 2 m, alive |
20 | Okamura [22] | 62 | M | SCNEC | Bm | 3 cm | NAC, resection, and irradiation | 20 m, dead |
21 | Yamaguchi [23] | 77 | F | NEC | Bi | N.A. | Resection and chemo. | 27 m, alive |
22 | Demoreuil [24] | 73 | M | LCNEC + Adenoca. | Bh-Bs | 3 cm | Resection and chemo. | 12 m, dead |
23 | Cho [25] | 59 | F | SCNEC | Bm | 3 cm | Resection | 6 m, dead |
24 | Sasatomi [26] | 76 | M | LCNEC | Bh-Bs | 5 cm | Resection | 21 days, dead |
25 | Ninomiya [27] | 75 | F | LCNEC | Bm | 3 cm | Resection | 14 m, alive |
26 | Park [28] | 75 | F | LCNEC | Bm | 2.7 cm | Resection and chemo. | 12 m, dead |
27 | Kihara [29] | 70 | F | SCNEC | Bh | 5 cm | Resection and chemo. | 10 m, alive |
28 | Current report | 79 | M | LCNEC + Adenoca. | Pm | 2.9 cm | Resection | 3 m, dead |