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Table 1 Clinical features of 45 reported pancreatic giant insulinomas

From: Giant insulinoma: report of a case and review of published reports

Variables

 

 Age (mean)

15–83 (57) years

 Sex (M:F)

1.14:1

 Tumor diameter (mean)

9–21 (12) cm

Location

 H/HB/B/BT/T/HBT/NA

3/1/2/13/22/1/3

Treatment for primary disease

 DP (+/− S)/DP+ RLM/DP+ ALM

23/2/2

 PD/TP/E/TR/biopsy/NO/NA

3/1/1/4/3/5/1

Metastatic sites

 Generalized/liver/LN, surround

6/7/12

 Recurrences/remnant/none

8/11/26

Recurrent sites

 Generalized/liver/local

2/4/1

Treatment of recurrences or remnant

 Surgery/Syst chemo/HACE/RT/none/NA

3/2/2/2/1/7

 Outcome (n)

Duration of follow-up (mean) months

 No disease recurrence (24)

3–276 (18)

 Alive with disease (6)

15–204 (48)

 Died of metastatic disease (10)

1–156 (24)

 Died of other disease (1)

NA

 NA (4)

NA

  1. H head, HB head and body, B body, BT body and tail, T tail, HBT head, body and tail, NA not available, DP distal pancreatectomy, +/− with/without, S splenectomy, RLM resection for liver metastases, ALM ablation of liver metastases, PD pancreaticoduodenectomy, TP total pancreatectomy, E enuclation, TR tumor resection, Biopsy biopsy of pancreatic or liver tumor, NO no operation, Generalized involvement of the liver and one or more of the following organs: adrenal glands, spleen, stomach, and colon, LN lymph node, Surround surrounding tissue, Remnant remnant disease, Syst chemo systemic chemotherapy, HACE hepatic arterial chemoembolization, RT radiation therapy