Table 1 The surgical cases of synchronous double cancers consisting of primary hepatocellular carcinoma and cholangiolocellular carcinoma
Author | Year | Age | Sex | HBsAg/HBsAb/HCVAb | AFP(ng/ml)/PIVKAII(mAU/ml) | CEA(ng/ml)/CA19-9(U/ml) | CoCC location/size | HCC location/size | Non-cancerous portion | Prognosis |
|---|---|---|---|---|---|---|---|---|---|---|
Matsuda [2] | 2006 | 70 | M | (−)/ND/(+) | NR/2155 | NR/NR | S7/2.2 cm | S4/4 cm | chronic hepatitis | 30 months alive without recurrence |
Ikeda [3] | 2010 | 64 | M | (+)/(−)/(−) | 39.7/202 | ND/ND | S8/2.2 cm | S8/1.7 cm | liver cirrhosis | 8 months alive without recurrence |
Kawano [4] | 2012 | 68 | F | (−)/(+)/(−) | 30.1/105 | 2.9/25.1 | S3/2 cm | S4/1.2 cm | ND | 41 months alive without recurrence |
Sunahara [5] | 2013 | 71 | M | (−)/(−)/(+) | NR/24458 | NR/NR | S6/0.8 cm | S4/2.8 cm | chronic hepatitis | 8 months alive without recurrence |
Takata [6] | 2014 | 71 | M | (−)/(+)/(−) | 333.5/140 | 0.6/ND | S3/1.5 cm | S7/4.5 cm | chronic hepatitis | 13 months alive without recurrence |
Our case | 2016 | 45 | M | (+)/ND/(−) | 2.7/317 | ND/ND | S7/1 cm | S6/2.3 cm | liver cirrhosis | 20 months died |