Fig. 4From: A hepatoid carcinoma of the pancreatic head a The tumor is composed of polygonal cells with granular eosinophilic cytoplasm, centrally located nuclei, and prominent nucleoli. Capillary (arrow) (H&E, ×400). b Immunohistochemical staining of the tumor for hepatocyte specific antigen (Hep Par 1)—cytoplasm of neoplastic cells is strongly positive whereas the centrally located nuclei with prominent nucleoli are negative (H&E, ×200)Back to article page