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Fig. 4 | Surgical Case Reports

Fig. 4

From: Intracystic papillary neoplasm with an associated mucinous adenocarcinoma arising in Rokitansky–Aschoff sinus of the gallbladder

Fig. 4

a The tumor consisted of subserosal multilocular cysts lined with columnar mucinous epithelium (hematoxylin and eosin). b The epithelium contained abundant intracytoplamic mucin and showed atypia with micropapillary growth and nuclear stratification with loss of polarity, which indicates neoplastic growth. c Stromal invasion of disorganized neoplastic cells were observed (black arrows). d The immunoreactivity against MUC2 was detected in the cytoplasm of the neoplastic epithelium

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