Fig. 4From: Intracystic papillary neoplasm with an associated mucinous adenocarcinoma arising in Rokitansky–Aschoff sinus of the gallbladder a The tumor consisted of subserosal multilocular cysts lined with columnar mucinous epithelium (hematoxylin and eosin). b The epithelium contained abundant intracytoplamic mucin and showed atypia with micropapillary growth and nuclear stratification with loss of polarity, which indicates neoplastic growth. c Stromal invasion of disorganized neoplastic cells were observed (black arrows). d The immunoreactivity against MUC2 was detected in the cytoplasm of the neoplastic epitheliumBack to article page