Table 2 Case reports of patients showing spontaneous HCV clearance within 1 year of liver transplant without postoperative anti-viral therapy
From: Spontaneous clearance of hepatitis C virus after liver transplantation: a report of four cases
Author (published year) | Age (years) | Sex | Preoperative HCV-RNA (log IU/ml) | HCV genotype | HCV treatment status | Rejection episodes | Immunosuppression | Time to HCV clearance after LT (days) | Postoperative morbidity | Transaminase elevation ahead of HCV clearance |
|---|---|---|---|---|---|---|---|---|---|---|
Doughty AL [6] (2000) | 49 | Male | 5.7 | N/A | N/A | Yes | MP, AZA, CSA | 383 | N/A | Yes |
Elsiesy H [2] (2015) | 32 | Female | 4.8 | 4 | Failure | None | FK506, CSA | 30 | N/A | Yes |
Kogiso T [7] (2015) | 50 | Female | 4.3 | 1 | Naïve | Yes | FK506, MMF, MP, CS | 87 | ACR | Yes |
52 | Male | 4.8 | 2 | Naïve | None | FK506, MMF, MP, CS | 115 | N/A | Yes | |
Our cases | ||||||||||
Case 1 | 66 | Male | 5.3 | 1b | Failure | None | Rituximab (preoperatively) FK506, MMF, MP, PSL | 152 | Sepsis | Yes |
Case 2 | 61 | Male | 2.3 | 2 | Failure | Yes | FK506, MMF, MP, PSL | 111 | Sepsis, ACR | Yes |
Case 3 | 55 | Male | 2.1 | 1b | Failure | None | FK506, MMF, MP, PSL | 177 | None | No |
Case 4 | 55 | Male | 5.5 | 1b | Failure | Yes | FK506, MMF, MP, PSL | 14 | ACR | No |