Table 1 Baseline characteristics of the four study patients
From: Spontaneous clearance of hepatitis C virus after liver transplantation: a report of four cases
Case 1 | Case 2 | Case 3 | Case 4 | |
|---|---|---|---|---|
Age (years) | 66 | 61 | 55 | 55 |
Sex | Male | Male | Male | Male |
MELD score (points) | 21.4 | 11 | 33 | 8 |
Child-Pugh (score) | B (9) | B (9) | C (13) | B (7) |
Preoperative HCV-RNA (log IU/ml) | 5.3 | 2.3 | 2.1 | 5.5 |
HCV treatment status | PEG-IFN → nonresponder (8 years in advance of LT) | IFN → terminated due to psychological side effect (21 years in advance of LT) | IFN → failure (9 years in advance of LT) | IFN → nonresponder (8 years advance of LT) |
Genotype | 1b | 2 | 1b | 1b |
Rejection episodes | None (RAI 2) | Yes (RAI 3) | None (RAI 1) | Yes (RAI 2) |
ABO blood type | Incompatible | Identical | Identical | Identical |
Immunosuppression | Rituximab (preoperatively) MMF. FK506, MP | MMF, FK506, MP, PSL | MMF, FK506, MP, PSL | MMF, FK506, MP, PSL |
Time to HCV clearance after LT (days) | 152 | 141 | 177 | 14 |
Re-emergence of HCV-RNA | None | None | None | Yes (day 85) |
Perioperative morbidity | Sepsis | Sepsis | ACR, steroid pulse | |
Follow-up periods (years) | 5 | 5 | 9 | 1 |