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Table 1 Clinical factors of the current case and 35 reviewed cases of EACC reported in Japan from 1990 to 2014

From: A case of adenoid cystic carcinoma of the esophagus

Year Age/sex Endoscopic appearance Biopsy Treatment Depth of invasion Lymph node metastasis Lymphatic invasion Vascular invasion Observation period (month) Outcome (cause of death)
Present 78/M Protruding ACC Surgery SM 2 Alive
1995 74/M Elevated ACC Surgery SM + + 12 Alive
1991 70/M Protruding ACC Surgery SM + N.A N.A
1995 59/M Protruding ACC Surgery SM 13 Alive
2011 67/F Protruding ACC Surgery SM N.A N.A
2012 64/M Protruding ACC Surgery SM N.A N.A
2005 81/M N.A N.A Surgery SM N.A N.A 69 Dead (other disease)
2005 69//M N.A N.A Surgery SM N.A N.A 51 Alive
1997 53/M Elevated SCC Surgery SM + + 36 Alive
1994 81/M Ulcerative SCC Surgery SM 26 Alive
2001 71/M Protruding SCC Surgery SM 41 Alive
2010 60/M Protruding SCC NAC + surgery SM 5 Alive
1997 81/M N.A N.A Surgery SM 22 Alive
2003 65/M Protruding N.A Surgery SM + 4 Dead (other disease)
1990 74/M Protruding SCC Surgery SM 30 Alive
1992 70/F Protruding N.A Surgery SM 142 Alive
1990 69/M Protruding SCC Surgery SM 6 Alive
1990 73/M Protruding SCC Surgery SM 18 Alive
1998 48/F Ulcerative ACC Surgery MP + + + 36 Alive
1996 57/M N.A N.A Chemotherapy + surgery MP + + 56 Alive
2005 68/M N.A N.A Surgery MP N.A N.A 2 Alive
1994 59/M Elevated SCC Surgery MP + 60 Alive
1991 64/M Ulcerative SCC Surgery MP 11 Alive
1992 59/M Ulcerative SCC Surgery MP + 42 Alive
1996 79/M Protruding Adeno Surgery MP N.A N.A 30 Alive
1994 61/M Ulcerative ACC Surgery AD N.A + 12 Dead (EACC)
2007 51/M Ulcerative ACC Surgery AD + 2 Alive
1994 71/M Protruding ACC Surgery AD + + + 5 Dead (other disease)
2005 41/M N.A N.A Radiation AD - N.A N.A 22 Dead (EACC)
1991 57/M Elevated SCC Surgery AD + N.A N.A N.A N.A
1996 68/F Protruding SCC Surgery AD N.A N.A N.A N.A
1992 64/M Elevated N.A Surgery AD + + 15 Dead (EACC)
1993 77/F Protruding ACC Chemotherapy AI (aorta) + N.A N.A 9 Dead (EACC)
1992 55/M Ulcerative SCC Surgery AI (trachea) + + + 7 Dead (EACC)
2005 84/M N.A N.A Surgery AI + N.A N.A 40 Alive
1997 70/F Protruding SCC Surgery N.A + N.A N.A 30 Dead (other disease)
  1. N.A not available, adeno adenocarcinoma, NAC neoadjuvant therapy, SM submucosa, MP muscle, AD adventitia, AI invasion to adjacent organ