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Fig. 4 | Surgical Case Reports

Fig. 4

From: A resected case of liver metastases from extra-adrenal retroperitoneal paraganglioma with von Recklinghausen’s disease 16 years after the initial surgery

Fig. 4

Histopathological findings (×200). Hematoxylin and eosin staining shows that although the Zellballen pattern typical of paraganglioma is not apparent, the tumors are composed of large and irregular nests of cells with anisokaryosis and basophilic cytoplasm, resulting in the final diagnosis of liver metastases from the paraganglioma (a). Immunohistochemical staining is positive for synaptophysin (b) and chromogranin A (c). The MIB-1 index is less than 0.5 % (d)

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