Skip to main content

Table 1 Clinical features of primitive neuroectodermal tumors of the pancreas

From: A peripheral primitive neuroectodermal tumor originating from the pancreas: a case report and review of the literature

  Presenting finding
Reference Age Sex Upper abdominal pain Other Tumor location Maximum tumor diameter Diagnostic procedure Lymph node metastasis Treatment Follow-up (month) Outcome
Danner [9] 17 M + Jaundice, nausea Head 90 Whipple resection 0/9 VDC/cisplatin + etoposide, RAD 33 NED
Luttges [8] 13 F Diarrhea Body 220 Whipple resection NA CHE NA NA
  31 M + Body NA Biopsy NA CHE NA NA
Bulchmann [10] 6 F + Anemia Head 60 Whipple resectiona 2/2 NP 6 DOD
O’Sullivan [11] 20 F NA Head 35 Whipple resection 4/34 CHE, RAD 30 AWD
Gemechu [12] 17 M Abdominal swelling Body 120 Resection NA NP 36 NED
Movahedi [2] 20 M + Jaundice Head 35 Whipple resection NA NP 27 AWD
  25 F + Jaundice Head NA Biopsy NA NA NA NA
  21 F + NA Head NA Whipple resection Positive NP DOC DOC
  25 F + Jaundice Head 80 Biopsy NA NA NA NA
  13 M + NA Head 60 Biopsy NA VDC 43 NED
  6 M + Jaundice Head 35 Whipple resection Positive VDC 48 DOD
Takeuchi [13] 10 F + Abdominal swelling Body 100 Biopsy NA CHE, surgery, AST 3 DOD
Perek [14] 31 M + Fever, abdominal swelling Head 120 Whipple resection None AI, ifosfamide, docetaxel 50 NED
Welsch [15] 33 M Nausea and vomiting Body 150 Distal pancreatecotomya NA VIDE, VAI, melaphalan + etoposide, AST 12 NED
Schutte [16] 2 F Precocious puberty Body 60 Distal pancreatecotomy None VDC/AI 12 NED
Wakao [17] 3 M + Abdominal swelling Head 82 Biopsy NA CITA, VDC/IE, MEC, surgery,a AST, RAD (30 Gy) 8 NED
Doi [18] 37 M Jaundice Head 60 Whipple resection Positive VDC, IE, RAD 6 NED
Menon [19] 8 F + NA Body 100 Biopsy NA Doxorubicin, RAD 19 DOD
Jing [20] 24 F NA NA Head 100 Resection NA CHE, RAD NA NA
Maxwell [21] 11 M Fatigue, anemia Head 98 Whipple resectiona NA VDC/IE 15 AWD
Mao [22] 13 F + Hyperglycemia Head 150 Resection (RUPT) None VAC, MAID, RAD 41 AWD
Reilly [23] 23 M + Nausea Body 58 Distal pancreatecotomya 1/24 NA NA NA
Dias [24] 25 F + Head 42 Whipple resection None VAI, VDC 8 DOD
Present case 22 M + Nausea, anemia Head 85 Whipple resectiona 4/15 CHE, RAD 12 AWD
  1. − absent, + present, AI actinomycin D (dactinomycin)/ifosfamide, AST autologous stem cell transplantation, AWD alive with disease, CHE chemotherapy (details unknown), IE ifosfamide/etoposide, DOC died of postoperative complication, DOD died of disease, F female, M male, MAID doxorubicin/dacarvazine/ifosfamide, MEC melphalan/etoposide/cisplatin, NA not available, NED no evidence of disease, NP not performed, RAD radiation, details unknown, RUPT resection of the uncinated process tumor, VAC vincristine/actinomycin D (dactinomycin)/cyclophosphamide, VAI vincristine/actinomycin D (dactinomycin)/ifosfamide, VAIA vincristine/doxorubicin/ifosfamide alternating with vincristine/actinomycin D (dactinomycin)/ifosfamide, VDC vincristine/doxorubicin/cyclophosphamide, VIDE vincristine/ifosfamide/doxorubicin/etoposide
  2. aThe tumor directly invaded another organ