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Fig. 2 | Surgical Case Reports

Fig. 2

From: A surgical case of eosinophilic angiocentric fibrosis of the lung

Fig. 2

Pathological analysis showed a a dense bronchocentric inflammatory infiltrate with numerous inflammatory cells and perivascular fibrosis. b Fibro-inflammatory lesion (perivascular fibrosis) surrounding the vessel in a whorled pattern. Numerous eosinophils infiltrate the lesion. c A fibrotic nodule with the “onion-skin” fibrosis pattern that is pathognomonic for eosinophilic angiocentric fibrosis. d Immunohistochemical staining for IgG4 revealed a large number of IgG4-positive cells (400 cells per high-power field)

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