A case of Gd-EOB-DTPA-enhanced MRI findings of huge AML. In the T1W in-phase image (A), the tumor itself is mixed intense in hypointense surroundings. In the in-phase hyperintense signal areas (white arrow), the loose signal in the T1W out-of-phase image (B) is consistent with the fat content (F). In the arterial phase image (C), a minor part of the tumor was remarkably enhanced (arrow) and this part is consistent with meandering blood vessels (G). In DWI, (D) MRI displays an obvious hyperintense signal, whereas in the hepatobiliary phase (E), it shows a homogenous hypointense signal. Major parts of the tumor are consistent with the smooth muscle cell component/components (H), and these lesions were positive for HMB-45 and Melan-A.