Fig. 6From: Sebaceous carcinoma of the breast: a case reportPathological findings of the resected specimen. a Macroscopically, the tumor, measuring 35Â mm in its greatest diameter, has no connection to the overlying skin or nipple. b The tumor shows solid growth of nests of various sizes in fibrous stroma. c The lesion consists of dense proliferation of relatively small, round cells and partially intermingled with cells with clear cytoplasm, indicating sebaceous differentiation (HE stain). d The tumor cells contain abundant Sudan Black B-positive lipid droplets in the cytoplasm. e On immunohistochemistry, 90% of the cells are positive for adipophilinBack to article page