Table 1 Clinical features of primitive neuroectodermal tumors of the pancreas
Presenting finding | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
Reference | Age | Sex | Upper abdominal pain | Other | Tumor location | Maximum tumor diameter | Diagnostic procedure | Lymph node metastasis | Treatment | Follow-up (month) | Outcome |
Danner [9] | 17 | M | + | Jaundice, nausea | Head | 90 | Whipple resection | 0/9 | VDC/cisplatin + etoposide, RAD | 33 | NED |
Luttges [8] | 13 | F | − | Diarrhea | Body | 220 | Whipple resection | NA | CHE | NA | NA |
31 | M | + | − | Body | NA | Biopsy | NA | CHE | NA | NA | |
Bulchmann [10] | 6 | F | + | Anemia | Head | 60 | Whipple resectiona | 2/2 | NP | 6 | DOD |
O’Sullivan [11] | 20 | F | NA | − | Head | 35 | Whipple resection | 4/34 | CHE, RAD | 30 | AWD |
Gemechu [12] | 17 | M | − | Abdominal swelling | Body | 120 | Resection | NA | NP | 36 | NED |
Movahedi [2] | 20 | M | + | Jaundice | Head | 35 | Whipple resection | NA | NP | 27 | AWD |
25 | F | + | Jaundice | Head | NA | Biopsy | NA | NA | NA | NA | |
21 | F | + | NA | Head | NA | Whipple resection | Positive | NP | DOC | DOC | |
25 | F | + | Jaundice | Head | 80 | Biopsy | NA | NA | NA | NA | |
13 | M | + | NA | Head | 60 | Biopsy | NA | VDC | 43 | NED | |
6 | M | + | Jaundice | Head | 35 | Whipple resection | Positive | VDC | 48 | DOD | |
Takeuchi [13] | 10 | F | + | Abdominal swelling | Body | 100 | Biopsy | NA | CHE, surgery, AST | 3 | DOD |
Perek [14] | 31 | M | + | Fever, abdominal swelling | Head | 120 | Whipple resection | None | AI, ifosfamide, docetaxel | 50 | NED |
Welsch [15] | 33 | M | − | Nausea and vomiting | Body | 150 | Distal pancreatecotomya | NA | VIDE, VAI, melaphalan + etoposide, AST | 12 | NED |
Schutte [16] | 2 | F | − | Precocious puberty | Body | 60 | Distal pancreatecotomy | None | VDC/AI | 12 | NED |
Wakao [17] | 3 | M | + | Abdominal swelling | Head | 82 | Biopsy | NA | CITA, VDC/IE, MEC, surgery,a AST, RAD (30 Gy) | 8 | NED |
Doi [18] | 37 | M | − | Jaundice | Head | 60 | Whipple resection | Positive | VDC, IE, RAD | 6 | NED |
Menon [19] | 8 | F | + | NA | Body | 100 | Biopsy | NA | Doxorubicin, RAD | 19 | DOD |
Jing [20] | 24 | F | NA | NA | Head | 100 | Resection | NA | CHE, RAD | NA | NA |
Maxwell [21] | 11 | M | − | Fatigue, anemia | Head | 98 | Whipple resectiona | NA | VDC/IE | 15 | AWD |
Mao [22] | 13 | F | + | Hyperglycemia | Head | 150 | Resection (RUPT) | None | VAC, MAID, RAD | 41 | AWD |
Reilly [23] | 23 | M | + | Nausea | Body | 58 | Distal pancreatecotomya | 1/24 | NA | NA | NA |
Dias [24] | 25 | F | + | − | Head | 42 | Whipple resection | None | VAI, VDC | 8 | DOD |
Present case | 22 | M | + | Nausea, anemia | Head | 85 | Whipple resectiona | 4/15 | CHE, RAD | 12 | AWD |